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While she is still nursing we keep it safe: azelaic acid, niacinamide, a gentle cleanser, mineral SPF because melasma loves the hormone shifts, and gentle in-clinic facials.” Valeria Marulanda, FNP-BC, Perfect B Aesthetics, Doral Once a provider evaluation confirms you are fully weaned and a good candidate, the stronger options typically include: Prescription tretinoin: a topical retinoid that speeds cell turnover, unclogs pores, and improves texture and post-acne marks over time