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Beyond, many of the observed changes occurred in patients with BD can be considered as signs of premature aging (telomere length, oxidative stress, inflammation, disruptions on biological clocks, epigenetic aging and mitochondrial dysfunction), as prior works hypothesize that accelerated aging process is potentially implicated in the development and course of BD [52]

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Upregulates growth factors such as VEGF (vascular endothelial growth factor) and FGF (fibroblast growth factor), accelerating wound repair