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The bone effects of amylin analogues also deserve investigation, as these drugs not only bind the amylin receptors AMY1R, AMY2R, and AMY3R, but also the calcitonin receptor, raising the possibility of direct effects on bone metabolism [10]

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We thank Paola Corradino (MultiMedica IRCCS) for data management, and Alessandra Panvini Rosati (MultiMedica Onlus) and Giuseppe Bertani (IRCCS–Arcispedale Santa Maria Nuova) for administrative assistance