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This is commonly achieved through the addition of ‘stealth’ molecules, like polyethylene glycol (PEG), to the surface of NPs, which enables them to evade clearance from the reticuloendothelial system, preventing opsonization and subsequent phagocytosis [17,18]

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In addition, FABP7 overexpression reverses reductions in BBB-associated proteins, including the tight junction components claudin-5 and occludin, and the water channel AQP4, induced by chronic unpredictable mild stress