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Interestingly, while NMN is known to be beneficial for aging-associated declines, this data suggests that NMN might have a neurotoxic effect in cases of axonal degeneration 54

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B12 Injections may be particularly beneficial for those with low energy, consistent fatigue, or low or suboptimal B12 levels, including older adults whose ability to absorb B12 from food and oral supplements naturally declines with age, individuals following plant-based diets, and those who have not responded well to oral B12 supplementation