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There is evidence that in patients with COPD, SPM of micro-sized fractions contributes to the modulation of the IL-6 signaling pathway in the direction of conventional signal transduction to T helper blood cells to regulate the inflammatory process and compensate for apoptotic changes [53]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 266.Madsen KL, Preisler N, Rasmussen J, Hedermann G, Olesen JH, Lund AM, et al