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Subsequently, the expression of Drp1 and Fis1 was up-regulated, while down-regulated expression of Opa1 and Mfn1 was observed, which indicated the effect of silibinin to enhance mitochondrial fission and to weaken mitochondrial fusion

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4 In another study evaluating topical glutathione’s role on UV-induced erythema, Grandi et al 9 found that subjects pre-treated with S-acyl glutathione 2% cream, a linoleic acid pre-conjugate, had a significantly lower minimal erythema dose compared to placebo, indicating UV protective properties ( p =0.0003)