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Berberine has been used in traditional Ayurvedic and Chinese medicine for thousands of years.[1] Berberine is a naturally occurring compound found in plants in the Berberis genus, most notably in the roots of Berberis aristata (AKA Indian Barberry)

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Peltekova VD, Wintle RF, Rubin LA, Amos CI, Huang Q, Gu X, Newman B, Van Oene M, Cescon D, Greenberg G, Griffiths AM, St George-Hyslop PH, and Siminovitch KA