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Other small studies on enzyme inducers such as phenobarbital, phenytoin, rifampicin, omeprazole and carbamazepine have suggested that their effect on 2E1 is not significant, and thus they are unlikely to be responsible for excessive NAPQI formation when taken concurrently with paracetamol 45, 132, 133

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On the contrary, plasma betaine was positively correlated to HDL-cholesterol and inversely associated with the above-mentioned risk factors, as well as with systolic and diastolic blood pressure