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Glutaminase 2, another target of p53, was also involved in ferroptosis via glutaminolysis in tumor cells ( Conversely, p53 suppressed ferroptosis by limiting the expression of dipeptidyl peptidase 4 (DPP4) (Xie et al., 2017) or by inducing the activity of cyclin-dependent kinase inhibitor 1A (CDKN1A/p21) (Tarangelo et al., 2018)