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The study also identified disease-specific hydroxymethylation regions (DhMRs) associated with positive epigenetic regulatory factors influencing gene expression, such as axonal guidance signaling, GABA receptor signaling, and Wnt/β-catenin/Sox, affecting neuronal development and function in HD pathogenesis (213)

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Copper on its own is a trace mineral with a well established nutritional role and a completely separate regulatory life, which is exactly what the Korean register shows when you ask it about copper