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Precisely, p53 has been shown to regulate glycolysis through repression of the glucose transporters GLUT1 and GLUT4 and upregulation of the gene TIGAR , which encodes a protein that degrades fructose-2,6-bisphosphate to block glycolysis (via the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate) (148, 149)

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The unique layered structure of GO enables extensive surface functionalization, allowing tailored properties from excellent adsorptive to hydrophobic/hydrophilic surfaces, and dimensional configurations spanning 0D to 3D nanostructures