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Orthobiologics and Injection therapies Platelet Rich Plasma (PRP) PRP therapy injects a high concentration of platelets extracted from the patient’s own blood into the knee joint, triggering the release of biologically active agents such as growth factors, cytokines, lysosomes and adhesion proteins to initiate and accelerate tissue healing

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Ethics declarations Ethics approval All animal procedures were conducted in accordance with the guidelines established by the National Institutes of Health Guide for the Care and Use of Laboratory Animals and were approved by the Institutional Animal Care and Use Committee (IACUC) at the University of Maryland School of Medicine (protocol number 00000006)