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Importantly, a mutation in PNPLA3 (rs738409), I148M, is the single greatest genetic risk factor for the development of FLD (64-67), however its precise function in neutral lipid metabolism is controversial (68, 69)

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In contrast to conventional GLP-1 peptides that primarily suppress appetite, 5-Amino-1MQ acts on metabolic pathways involved in fat storage and energy utilization, which has led to its growing interest in advanced studies on body composition and longevity