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10.1016/j.smim.2023.101728 15

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In support of this, there was a prominent transcriptional upregulation in the BHMT2 betaine homocysteine methyl transferase 2, by 3.6 and 3.2 fold in the BG and HG environment, respectively, a gene that transfers methyl groups from betaine to homocysteine to regenerate methionine (Table 2.)