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Colocalization of the Wnt pathway and GPX2, as well as the regulation of GPX2 through Wnt signaling, suggest that GPX2 plays a role in the continuous self-renewal of the intestinal epithelium and thus in the homeostasis of the intestinal mucosa (Pérez et al., 2017)

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Thus, contracture was permanent in the control rats and also evident with actively assisted (forced) extension