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Programmable extracellular vesicles for macromolecule delivery and genome modifications

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In STZ-diabetic gastroparesis model (C57BL/6, week 8), intranasal oxytocin at 2µg twice daily for 4 weeks: gastric emptying (scintigraphic 4h solid meal retention) fell from 48±8% (diabetic+vehicle) to 28±6% (oxytocin) versus 12±4% naïve

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