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Lip-1 is rapidly metabolized and exhibits a short elimination half-life, which may compromise its therapeutic efficacy and reduce patient compliance due to the need for frequent dosing ( While high-dose α-tocopherol supplementation may exert therapeutic effects in specific contexts, the current evidence on the safety profile of high-dose α-tocopherol supplementation is still inconclusive

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This finding of the role for B-1 B cells “demonstrates the potential for targeting the natural antibody repertoire in considering therapeutic strategies for Type 1 diabetes,” said John Kearney, Ph.D., a professor in the UAB Department of Microbiology, who led the study

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