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Therefore, expectations should be realistic and supported by proper skincare practices such as sun protection, consistent skin care, and overall health maintenance

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The production and excretion of high concentrations of lactate are also associated with the recruitment of immune cells and promotion of differentiation of immunosuppressive cell types, such as regulatory T cells (Treg), alternatively activated (M2) macrophages and myeloid-derived suppressor cells (MSDC) which further suppress antitumour immune responses [464,466]