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This platform utilizes extensive tumor and normal transcriptome datasets, paired with sophisticated analytical tools, to detect tumor antigens arising from alternative splicing (AS), a mechanism where various mRNA isoforms are produced from a single gene (Baralle and Giudice, 2017)

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Kahn also calls the peptide category a “bit of a gray zone,” given its uncertain regulatory status, but says she wants to emphasize that patients cannot simply buy peptides from compounding pharmacies