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These nightly disruptions rob many people of restorative sleep and can dramatically affect energy level, mood, and overall quality of life

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Since renal NE is an established neurochemical marker of RDN effectiveness [20, 21, 39, 54,55,56], the beneficial effects on the pressure-natriuresis relationship might depend on inhibition of inappropriately high RSNA and of its direct or indirect influence on the tubular water and sodium reabsorption