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Peptide Storage & Handling Guide External Research References Molecular engineering approaches to half-life extension of therapeutic biomolecules (PMC) Prediction of Half-Life Extension of Peptides via Serum Albumin Binding (PubMed) Molecular analysis and therapeutic applications of human serum albumin–fatty acid interactions (PubMed) Probing the Binding Mechanism of Acylated Peptides to Human Serum Albumin (PubMed) Artificial lipidation of proteins and peptides: from mechanism to clinical applications (PubMed) Strategies for extending the half-life of biotherapeutics: successes and complications (Expert Opinion on Biological Therapy) Final Thoughts Peptide half-life is much more complicated than simply asking: “How long does this peptide last?” The answer depends on the molecule’s structure, biological environment, clearance mechanisms, formulation, species, route of administration, and experimental conditions