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Gene expression studies suggest GHK-Cu can influence a broad set of genes involved in tissue remodeling, with research groups reporting effects on dozens of genes tied to collagen production, extracellular matrix turnover, antioxidant defense, and wound repair

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Whereas its utilisation in peroxide control is soon made good via interlocking GSH peroxidase-GSH reductase, NADPH-NADP, and glucose 6 phosphate-ribose 5 phosphate shuttles, it is permanently excreted from cells in conjugates with RXS (Figure 2) (21, 170)