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However, there is evidence that free-radicals such as NO cause rapid damage to certain cell macromolecules that are involved in the ETC system, which in turn will decrease production of ATP and may be implicated in cytotoxic effects in the central nervous system (Lizasoain et al., 1996)

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Common research-planning timeline (anecdotal aggregation) Window Weeks 1-2 What is commonly reported Improved sleep depth, more vivid dreams, mild water retention