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SCFAs are the products of fermentation of dietary fibers by the intestinal flora at the site of the cecal colon, which primarily consists of acetate, propanoate, butyrate, isobutyrate, valerate, isovalerate, hexanoate, and isohexanoate ( 3.3 The role of SCFAs in MetS The core of MetS development is insulin resistance, which could be affected by gut microbiota-derived metabolites

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Fat metabolism involves breaking down stored fat into fatty acids, which are then transported into cells to be oxidised and used as fuel