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“They last for only about eight hours, so you can take a dose in the morning and one in the mid-afternoon, and it’s gone overnight.” Long-acting TRT absorption rates Intramuscular injection (taken every one to four weeks, depending on dose): max absorption at 36–48 hours, with some outliers at 5–10 days Subdermal pellets (taken every 3-6 months, depending on dose): max absorption at 2-4 weeks Long-acting testosterone injections or pellets do not mimic your natural circadian rhythm
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