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It is important to note that this imbalance correlates with the extent of injury and the impact of the pathophysiology of brain injury [44-46]

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This aberrant oxidative phosphorylation in astrocytes results in lipid droplet accumulation, suggesting a clear importance of lipid metabolism as a mechanism underlying AD pathology, where astrocytic mitochondrial dysfunction progressively induces neuroinflammation and neurodegeneration (114)