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Separately, in a larger, longer-term prospective Swedish cohort ( n 3236 participants with median follow-up of 21·4 years), higher plasma levels of ergothioneine were associated with significantly lower risk of coronary disease, cardiovascular mortality and overall mortality (hazard ratios per 1 sd increment of ergothioneine were 0·85, 0·79 and 0·86, respectively) (80)