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The β-globin gene family members include the embryonic globin ∊, the fetal globin γ, and two globins expressed primarily during the adult period, δ and β

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In a phase I trial in patients with advanced solid tumors and lymphomas, it showed biological activity (induction of interferon-stimulated gene expression and immune infiltration) but relatively limited clinical responses, highlighting the need to optimize dose, route of administration, and combination regimens (e.g., with PD-1 inhibitors) [452,465,466]