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Materials and methods Mice The BAC-STAU1 mouse model was developed by the University of Utah Transgenic Mouse Core by pronuclear microinjection of a non-linearized human Staufen1 bacterial artificial chromosome (BAC) construct (BAC-STAU1 clone RP11-120I11, BACPAC Resources) into fertilized oocytes sourced from mice with a B6/D2 mixed hybrid background (B6D2F1J, The Jackson Laboratory stock #100006)

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