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Subsequently, investigators recognized that small increases in plasma Hcy concentrations were associated with folate, vitamin B 12 , or vitamin B 6 deficiency and with increased risk of cardiovascular disease, neural tube defects, and various other diseases found in the general population (10, 11, 12, 13)

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Further, it then plays a big role in signaling tissue remodeling which removes damaged/scarred tissue and generates new, healthy tissue