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4 Challenges and perspectives of ferroptosis in kidney diseases Ferroptosis, an iron-dependent regulated cell death driven by lipid peroxidation, has emerged as a central pathogenic mediator in kidney diseases—an organ uniquely susceptible to redox imbalance due to its high metabolic activity, abundant iron handling, and structural heterogeneity (276, 277)

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Role of adaptive and innate immune cells in chronic fatigue syndrome/myalgic encephalomyelitis