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Figure 4 In various experimental systems, including two-dimensional cultures, three-dimensional spheroids, organoids, xenografts, residual disease models, and patient-derived samples, DTP cells consistently share three defining properties: the ability to survive high or prolonged exposure to drugs, entry into a reversible slow-cycling or inactive state, and recovery of proliferative capacity and drug sensitivity after treatment withdrawal

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In turn, it has been observed that administration of said analog (recombinant human GHRH-1,44-amide) in older men, shortened the time required to walk 30 m and ascend four flights of stairs