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Cancer cell biology research examining IGF1R-driven proliferation often uses LR3 as a standard reagent precisely because the dose-response across a multi-day proliferation assay is more interpretable when the ligand is stable in the media

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Pulmonary Artery Hypertension (PAH) PAH is characterized by elevated pulmonary artery pressure and increased pulmonary vascular resistance, which can lead to maladaptive right ventricular remodeling, heart failure, and even death [105,106]