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Despite the remarkable advances in artificial pancreas systems, continuous glucose monitoring (CGM) sensors and novel insulin analogs over the last years, achieving adequate glucose control remains challenging for many pediatric and adult patients with T1D [51] due to several factors, such as weight gain, hypoglycemia (including exercise-induced hypoglycemia), high glycemic variability, postprandial glucose excursions (early postprandial hyperglycemia and late postprandial hypoglycemia), possible presence of binge eating disorder and disordered eating behaviors, as well as other factors that can negatively affect physical activity routines and adherence to insulin therapy (e.g., fear of hypoglycemia, psychological factors, and poor acceptance of the disease) [45,52,53,54,55,56,57]
